Reverse flux through cardiac NADP+-isocitrate dehydrogenase under normoxia and ischemia
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منابع مشابه
Reverse flux through cardiac NADP(+)-isocitrate dehydrogenase under normoxia and ischemia.
Little is known about the role of mitochondrial NADP(+)-isocitrate dehydrogenase (NADP(+)-ICDH) in the heart, where this enzyme shows its highest expression and activity. We tested the hypothesis that in the heart, NADP(+)-ICDH operates in the reverse direction of the citric acid cycle (CAC) and thereby may contribute to the fine regulation of CAC activity (Sazanov and Jackson, FEBS Lett 344: 1...
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ژورنال
عنوان ژورنال: American Journal of Physiology-Heart and Circulatory Physiology
سال: 2002
ISSN: 0363-6135,1522-1539
DOI: 10.1152/ajpheart.00287.2002